HP
haptoglobin
别名:
BP, HP2ALPHA2, HPA1S
物种:
Human HP (3240), Mouse Hp (15439), Rat Hp (24464), Zebrafish hp (566096), fruit fly hp (251278), domestic cat HP (100144610), dog HP (479668), Domestic Rabbit HP (100008816), sheep HP (101102413), cow HP (280692) ...展开
UniProtKB ID:
基因ID:
- Human(3240) Summary: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(15439) haptoglobin
- Rat(24464) haptoglobin
- Zebrafish(566096) haptoglobin
- fruit fly(251278) humped
- domestic cat(100144610) haptoglobin
- dog(479668) haptoglobin
- Domestic Rabbit(100008816) haptoglobin
- sheep(101102413) haptoglobin
- cow(280692) haptoglobin
- naked mole-rat(101705743) haptoglobin
- domestic guinea pig(100721435) haptoglobin
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Antibodies
货号
说明
物种反应性
应用
Anti-Hp Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
Anti-Haptoglobin antibody produced in rabbit, IgG fraction of antiserum, lyophilized powder,
物种反应性
human
应用
ELISA
Anti-Haptoglobin antibody, Mouse monoclonal, clone HG-36, purified from hybridoma cell culture,
物种反应性
human
应用
ELISA
dot blot
immunoprecipitation (IP)
western blot
dot blot
immunoprecipitation (IP)
western blot
Anti-Haptoglobin (HP) antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Proteins
货号
说明
物种
esiRNA
货号
说明
物种