HIRA
histone cell cycle regulator
别名:
DGCR1, TUP1, TUPLE1
物种:
Human HIRA (7290), Mouse Hira (15260), Rat Hira (363849), Thale Cress HIRA (823578), Domestic Rabbit HIRA (100352472), sheep HIRA (101120607), cow HIRA (511514), domestic cat HIRA (101098170), Horse HIRA (100052845), dog HIRA (486424) ...展开
UniProtKB ID:
基因ID:
- Human(7290) Summary: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
- Mouse(15260) histone cell cycle regulation defective homolog A (S. cerevisiae)
- Rat(363849) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Thale Cress(823578) protein HIRA
- Domestic Rabbit(100352472) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- sheep(101120607) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- cow(511514) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- domestic cat(101098170) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Horse(100052845) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- dog(486424) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Zebrafish(568076) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- chicken(374074) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- fruit fly(31680) CG12153 gene product from transcript CG12153-RA
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Antibodies
货号
说明
物种反应性
应用
抗-HIRA抗体，克隆WC119, clone WC119, from mouse,
物种反应性
human, mouse
应用
immunoprecipitation (IP)
western blot
western blot
Anti-HIRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-HIRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-HIRA (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti- HIRA antibody produced in rabbit, ,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
western blot