GCLC
glutamate-cysteine ligase, catalytic subunit
别名:
GCL, GCS, GLCL, GLCLC
物种:
Human GCLC (2729), Mouse Gclc (14629), Rat Gclc (25283), fruit fly Gclc (53581), Zebrafish gclc (326857), dog GCLC (609822), domestic guinea pig Gclc (100726181), naked mole-rat Gclc (101718793), Domestic Rabbit GCLC (100342383), cow GCLC (512468) ...展开
UniProtKB ID:
基因ID:
- Human(2729) Summary: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
- Mouse(14629) glutamate-cysteine ligase, catalytic subunit
- Rat(25283) glutamate-cysteine ligase, catalytic subunit
- fruit fly(53581) Glutamate-cysteine ligase catalytic subunit
- Zebrafish(326857) glutamate-cysteine ligase, catalytic subunit
- dog(609822) glutamate-cysteine ligase, catalytic subunit
- domestic guinea pig(100726181) glutamate-cysteine ligase, catalytic subunit
- naked mole-rat(101718793) glutamate-cysteine ligase, catalytic subunit
- Domestic Rabbit(100342383) glutamate-cysteine ligase, catalytic subunit
- cow(512468) glutamate-cysteine ligase, catalytic subunit
- sheep(101114822) glutamate-cysteine ligase, catalytic subunit
- domestic cat(101096568) glutamate-cysteine ligase, catalytic subunit
- Horse(100056731) glutamate-cysteine ligase, catalytic subunit
- chicken(421894) glutamate-cysteine ligase, catalytic subunit
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-GCLC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-GCLC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GCLC antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Anti-GCLC Antibody, clone 2H13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
货号
说明
物种