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Merck
CN

CYP51A1

cytochrome P450, family 51, subfamily A, polypeptide 1

别名:
CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1
物种:
Human CYP51A1 (1595), chicken CYP51A1 (420548), dog CYP51A1 (475225), cow CYP51A1 (505060)
UniProtKB ID:
Q16850, A4D1F8, B2RAI4, B4DJ55, O00770, O00772, Q16784, Q8N1A8
基因ID:
  • Human(1595) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • chicken(420548) cytochrome P450, family 51, subfamily A, polypeptide 1
  • dog(475225) cytochrome P450, family 51, subfamily A, polypeptide 1
  • cow(505060) cytochrome P450, family 51, subfamily A, polypeptide 1

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Antibodies

货号
说明
物种反应性
应用
MABS1259
抗-CYP51A1抗体，克隆N6-P2H5*G8, clone N6-P2H5*G8, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
HPA043508
Anti-CYP51A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
HPA041325
Anti-CYP51A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
SAB2107501
Anti-CYP51A1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
dog, guinea pig, horse, human, rat
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
K1003
酮康唑, 99.0-101.0% (EP, titration),
物种
mouse, human, rat
UC280
酮康唑, ,
物种
mouse, human, rat

esiRNA

货号
说明
物种
EHU105301
MISSION® esiRNA, targeting human CYP51A1, LRRD1,
物种
human