CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
别名:
CP46, CYP46
物种:
Human CYP46A1 (10858), Mouse Cyp46a1 (13116), Rat Cyp46a1 (362782), chicken CYP46A1 (423450), Zebrafish cyp46a1 (553543), cow CYP46A1 (506438), dog CYP46A1 (480432)
UniProtKB ID:
基因ID:
- Human(10858) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
- Mouse(13116) cytochrome P450, family 46, subfamily a, polypeptide 1
- Rat(362782) cytochrome P450, family 46, subfamily a, polypeptide 1
- chicken(423450) cytochrome P450, family 46, subfamily A, polypeptide 1
- Zebrafish(553543) cytochrome P450, family 46, subfamily A, polypeptide 1
- cow(506438) cytochrome P450, family 46, subfamily A, polypeptide 1
- dog(480432) cytochrome P450, family 46, subfamily A, polypeptide 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-CYP46A1 Antibody, clone 1C20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-CYP46A1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
抗胆固醇-24羟化酶抗体，克隆1A7, clone 1A7, from mouse,
物种反应性
human, mouse, rabbit, rat
应用
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Monoclonal Anti-CYP46A1 antibody produced in mouse, clone 2B5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CYP46A1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, goat, guinea pig, horse, human, mouse, rat
应用
western blot