CFB
complement factor B
别名:
AHUS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2
物种:
Human CFB (629), Mouse Cfb (14962), Rat Cfb (294257), cow CFB (514076), Horse CFB (100051124), dog CFB (100688056), sheep CFB (101115072), Zebrafish cfb (30604), domestic cat CFB (101093018), naked mole-rat Cfb (101725137)
UniProtKB ID:
基因ID:
- Human(629) Summary: This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008]
- Mouse(14962) complement factor B
- Rat(294257) complement factor B
- cow(514076) complement factor B
- Horse(100051124) complement factor B
- dog(100688056) complement factor B
- sheep(101115072) complement factor B
- Zebrafish(30604) complement factor B
- domestic cat(101093018) complement factor B
- naked mole-rat(101725137) complement factor B
- domestic guinea pig(100715616) complement factor B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-CFB antibody produced in rabbit, Ab3, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
ANTI-CFB antibody produced in rabbit, Ab4, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-CFAB Bb (Cleaved-Lys260) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
western blot
western blot
esiRNA
货号
说明
物种