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Merck
CN

ANK3

ankyrin 3, node of Ranvier (ankyrin G)

别名:
ANKYRIN-G
物种:
UniProtKB ID:
基因ID:
  • Human(288) Summary: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(11735) ankyrin 3, epithelial
  • Rat(361833) ankyrin 3, node of Ranvier (ankyrin G)
  • naked mole-rat(101719656) ankyrin 3, node of Ranvier (ankyrin G)
  • domestic guinea pig(100734552) ankyrin 3, node of Ranvier (ankyrin G)
  • sheep(101120296) ankyrin 3, node of Ranvier (ankyrin G)
  • chicken(396309) ankyrin 3, node of Ranvier (ankyrin G)
  • Horse(100062775) ankyrin 3, node of Ranvier (ankyrin G)
  • domestic cat(101097842) ankyrin 3, node of Ranvier (ankyrin G)
  • dog(479215) ankyrin 3, node of Ranvier (ankyrin G)
  • cow(511203) ankyrin 3, node of Ranvier (ankyrin G)

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Antibodies

货号
说明
物种反应性
应用
抗-锚蛋白-G抗体,克隆N106/36, clone N106/36, from mouse,
物种反应性
rat
应用
immunohistochemistry
Monoclonal Anti-Ankyrin G antibody produced in mouse, clone S106-20, purified immunoglobulin,
物种反应性
human, mouse, rat
应用
western blot
Anti-ANK3 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
Anti-Ankyrin-G Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
affinity binding assay
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-Ankyrin G - Biotin antibody produced in mouse, clone S106-20, purified immunoglobulin,
物种反应性
human, mouse, rat
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Ank3,
物种
mouse
MISSION® esiRNA, targeting human ANK3,
物种
human