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Key Documents

Safety Information

SAB2700261

Sigma-Aldrich

Anti-LIG3 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

LIG2, LIG3

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5 G
CN¥829.76
250 G
CN¥2,203.86
500 G
CN¥3,796.61

CN¥829.76


Available to ship onApril 07, 2025Details



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5 G
CN¥829.76
250 G
CN¥2,203.86
500 G
CN¥3,796.61

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CN¥829.76


Available to ship onApril 07, 2025Details


biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable
western blot: 500-3000

NCBI accession no.

UniProt accession no.

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This Item
704105900820900822
density

1.145 g/mL at 25 °C

density

-

density

-

density

-

mp

60 °C (lit.)

mp

56-64 °C, 60 °C (lit.)

mp

-

mp

-

mol wt

average Mn 80,000

mol wt

Mn 40,000-50,000, Mw 48,000-90,000, average Mn 45,000

mol wt

-

mol wt

-

impurities

<0.5% water

impurities

-

impurities

≤0.5 Residual monomer (GC), ≤0.5% Residual Water content (colormetric titration), ≤100 ppm Tin (AAS)

impurities

≤0.5% Residual monomer (GC), ≤0.5% Residual water content (colormetric titration), ≤100 ppm Tin (AAS)

Mw/Mn

<2

Mw/Mn

-

Mw/Mn

-

Mw/Mn

-

Immunogen

Recombinant fragment corresponding to a region within amino acids 116 and 433 of DNA ligase 3 according to NP_039269

Application

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biochem/physiol Actions

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 3 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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