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704105

Sigma-Aldrich

Polycaprolactone

average Mn 45,000

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Synonym(s):
2-Oxepanone homopolymer, 6-Caprolactone polymer
Linear Formula:
(C6H10O2)n
UNSPSC Code:
12162002
NACRES:
NA.21

form

pellets

Quality Level

100

melt index

1.8 g/10 min (80 °C, 44 psi)

mol wt

Mn 40,000-50,000
Mw 48,000-90,000
average Mn 45,000

mp

56-64 °C
60 °C (lit.)

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General description

Polycaprolactone (PCL) is a semi-crystalline linear resorbable aliphatic polyester that is composed of repeating units of hexanoate. It has good mechanical properties, miscibility, and biodegradability. PCL is a soft and hard-tissue compatible material that can be used in sutures and drug delivery systems.

Application

PCL can form a nanocomposite with graphene for the fabrication of biodegradable systems for bone tissue engineering.

Features and Benefits

Biodegradable polymer
Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.

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WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A novel degradable polycaprolactone networks for tissue engineering
Kweon H, et al.
Biomaterials, 24(5), 801-808 (2003)
Covalently linked biocompatible graphenepolycaprolactone composites for tissue engineering
Sayyar S, et al.
Carbon, 52(5), 296-304 (2013)
Synthesis of polycaprolactone: a review
Labet M and Thielemans W
Chemical Society Reviews, 38(12), 3484-3504 (2009)
Properties of thermoplastic blends: starch-polycaprolactone
Averous L, et al.
Polymer, 41(11), 4157-4167 (2000)
Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering
Williams JM, et al.
Biomaterials, 26(23), 4817-4827 (2005)
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