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Merck
CN

ZP2

zona pellucida glycoprotein 2 (sperm receptor)

别名:
ZPA, Zp-2
物种:
UniProtKB ID:
基因ID:
  • Human(7783) Summary: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. [provided by RefSeq, Jul 2008]
  • Mouse(22787) zona pellucida glycoprotein 2
  • Rat(81828) zona pellucida glycoprotein 2 (sperm receptor)
  • cow(280963) zona pellucida glycoprotein 2 (sperm receptor)
  • domestic cat(493977) zona pellucida glycoprotein 2 (sperm receptor)
  • dog(403988) zona pellucida glycoprotein 2 (sperm receptor)
  • domestic guinea pig(100713508) zona pellucida glycoprotein 2 (sperm receptor)
  • naked mole-rat(101706160) zona pellucida glycoprotein 2 (sperm receptor)
  • Domestic Rabbit(100009069) zona pellucida glycoprotein 2 (sperm receptor)
  • sheep(101123598) zona pellucida glycoprotein 2 (sperm receptor)
  • chicken(427006) zona pellucida glycoprotein 2 (sperm receptor)

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Antibodies

货号
说明
物种反应性
应用
Anti-ZP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
抗-ZP-2抗体,克隆IE-3, clone IE-3, from rat,
物种反应性
mouse
应用
ELISA
immunofluorescence

immunoprecipitation (IP)

western blot
Anti-ZP2 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
human
应用
western blot
Monoclonal Anti-ZP2 antibody produced in mouse, clone 2B9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human ZP2,
物种
human
MISSION® esiRNA, targeting mouse Zp2,
物种
mouse