WNT1
wingless-type MMTV integration site family, member 1
别名:
BMND16, INT1, OI15
物种:
Human WNT1 (7471), Mouse Wnt1 (22408), Rat Wnt1 (24881), cow WNT1 (540662), naked mole-rat Wnt1 (101722636), Zebrafish wnt1 (30128), dog WNT1 (486560), domestic guinea pig Wnt1 (100717026), domestic cat WNT1 (101094190), sheep WNT1 (101103389)
UniProtKB ID:
基因ID:
- Human(7471) Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]
- Mouse(22408) wingless-related MMTV integration site 1
- Rat(24881) wingless-type MMTV integration site family, member 1
- cow(540662) wingless-type MMTV integration site family, member 1
- naked mole-rat(101722636) wingless-type MMTV integration site family, member 1
- Zebrafish(30128) wingless-type MMTV integration site family, member 1
- dog(486560) wingless-type MMTV integration site family, member 1
- domestic guinea pig(100717026) wingless-type MMTV integration site family, member 1
- domestic cat(101094190) wingless-type MMTV integration site family, member 1
- sheep(101103389) wingless-type MMTV integration site family, member 1
- Horse(100058859) wingless-type MMTV integration site family, member 1
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Antibodies
货号
说明
物种反应性
应用
Anti-WNT1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
抗-WNT1抗体，克隆10C8, ascites fluid, clone 10C8, from mouse,
物种反应性
human, mouse
应用
flow cytometry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
esiRNA
货号
说明
物种