WISP2
WNT1 inducible signaling pathway protein 2
别名:
CCN5, CT58, CTGF-L
物种:
Human WISP2 (8839), Mouse Wisp2 (22403), Rat Wisp2 (29576), dog WISP2 (610928), domestic cat WISP2 (101091930), Zebrafish wisp2 (100007759), cow WISP2 (534658), chicken WISP2 (419192), sheep WISP2 (101106613), domestic guinea pig Wisp2 (100721143)
UniProtKB ID:
基因ID:
- Human(8839) Summary: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq, Jul 2008]
- Mouse(22403) WNT1 inducible signaling pathway protein 2
- Rat(29576) WNT1 inducible signaling pathway protein 2
- dog(610928) WNT1 inducible signaling pathway protein 2
- domestic cat(101091930) WNT1 inducible signaling pathway protein 2
- Zebrafish(100007759) WNT1 inducible signaling pathway protein 2
- cow(534658) WNT1 inducible signaling pathway protein 2
- chicken(419192) WNT1 inducible signaling pathway protein 2
- sheep(101106613) WNT1 inducible signaling pathway protein 2
- domestic guinea pig(100721143) WNT1 inducible signaling pathway protein 2
- naked mole-rat(101706687) WNT1 inducible signaling pathway protein 2
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Antibodies
货号
说明
物种反应性
应用
Monoclonal Anti-WISP2 antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-WISP2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Proteins
货号
说明
物种
CTGFL-WISP-2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
物种
human