VRK1
vaccinia related kinase 1
别名:
PCH1, PCH1A
物种:
Human VRK1 (7443), Mouse Vrk1 (22367), Rat Vrk1 (362779), domestic guinea pig Vrk1 (100728382), naked mole-rat Vrk1 (101713744), chicken VRK1 (423443), Zebrafish vrk1 (406694), dog VRK1 (490848), domestic cat VRK1 (101091879), cow VRK1 (618880)
UniProtKB ID:
基因ID:
- Human(7443) Summary: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008]
- Mouse(22367) vaccinia related kinase 1
- Rat(362779) vaccinia related kinase 1
- domestic guinea pig(100728382) vaccinia related kinase 1
- naked mole-rat(101713744) vaccinia related kinase 1
- chicken(423443) vaccinia related kinase 1
- Zebrafish(406694) vaccinia related kinase 1
- dog(490848) vaccinia related kinase 1
- domestic cat(101091879) vaccinia related kinase 1
- cow(618880) vaccinia related kinase 1
- sheep(101122310) vaccinia related kinase 1
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Antibodies
货号
说明
物种反应性
应用
抗-VRK1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Vaccinia related kinase-1 Antibody, C-Terminus, from rabbit,
物种反应性
human
应用
ChIP
western blot
western blot
Anti-Vaccinia related kinase-1 Antibody, N-Terminus, from rabbit,
物种反应性
human
应用
ELISA
western blot
western blot
Monoclonal Anti-VRK1 antibody produced in mouse, clone 4F9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
Proteins
货号
说明
物种
VRK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human