USP2
ubiquitin specific peptidase 2
别名:
UBP41, USP9
物种:
Human USP2 (9099), Mouse Usp2 (53376), Rat Usp2 (115771), domestic cat USP2 (101097757), dog USP2 (608188), chicken USP2 (395766), domestic guinea pig Usp2 (100716929), naked mole-rat Usp2 (101712304), cow USP2 (522980), sheep USP2 (101109478)
UniProtKB ID:
基因ID:
- Human(9099) Summary: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- Mouse(53376) ubiquitin specific peptidase 2
- Rat(115771) ubiquitin specific peptidase 2
- domestic cat(101097757) ubiquitin specific peptidase 2
- dog(608188) ubiquitin specific peptidase 2
- chicken(395766) ubiquitin specific peptidase 2
- domestic guinea pig(100716929) ubiquitin specific peptidase 2
- naked mole-rat(101712304) ubiquitin specific peptidase 2
- cow(522980) ubiquitin specific peptidase 2
- sheep(101109478) ubiquitin specific peptidase 2
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Antibodies
货号
说明
物种反应性
应用
Anti-USP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-USP2 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-USP2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot