UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J
- Human(54575) Summary: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines. [provided by RefSeq, Jul 2008]
- Mouse(394430) UDP glycosyltransferase 1 family, polypeptide A10
- domestic guinea pig(100721632) UDP glucuronosyltransferase 1 family, polypeptide A10
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Antibodies
Anti-UGT1A10 Antibody, clone 20H1, clone 20H1, from mouse,
human
immunohistochemistry
western blot
western blot