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Merck
CN

TNK2

tyrosine kinase, non-receptor, 2

别名:
ACK, ACK-1, ACK1, p21cdc42Hs
物种:
UniProtKB ID:
基因ID:
  • Human(10188) Summary: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(51789) tyrosine kinase, non-receptor, 2
  • Rat(303882) tyrosine kinase, non-receptor, 2
  • naked mole-rat(101701156) tyrosine kinase, non-receptor, 2
  • sheep(101122917) tyrosine kinase, non-receptor, 2
  • cow(280710) tyrosine kinase, non-receptor, 2
  • domestic guinea pig(100715920) tyrosine kinase, non-receptor, 2
  • domestic cat(101098817) tyrosine kinase, non-receptor, 2
  • chicken(431014) tyrosine kinase, non-receptor, 2
  • dog(488025) tyrosine kinase, non-receptor, 2

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ELISA

货号
说明
物种
磷酸酪氨酸TNK2 /活化CDC42激酶1 ELISA试剂盒, ,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-Tnk2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-phospho-ACK1 (Tyr284) Antibody, Upstate®, from rabbit,
物种反应性
human
应用
dot blot
inhibition assay

western blot
Anti-TNK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-TNK2 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-phospho-ACK1 (pTyr284) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

货号
说明
物种
ACK1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Tnk2,
物种
mouse
MISSION® esiRNA, targeting human TNK2,
物种
human