TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
CD258, HVEML, LIGHT, LTg, TR2
Human TNFSF14 (8740), Mouse Tnfsf14 (50930), Rat Tnfsf14 (301133), domestic guinea pig Tnfsf14 (100725147), dog TNFSF14 (611306), naked mole-rat Tnfsf14 (101725636), cow TNFSF14 (505521), domestic cat TNFSF14 (101096542)
- Human(8740) Summary: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(50930) tumor necrosis factor (ligand) superfamily, member 14
- Rat(301133) tumor necrosis factor (ligand) superfamily, member 14
- domestic guinea pig(100725147) tumor necrosis factor (ligand) superfamily, member 14
- dog(611306) tumor necrosis factor (ligand) superfamily, member 14
- naked mole-rat(101725636) tumor necrosis factor (ligand) superfamily, member 14
- cow(505521) tumor necrosis factor (ligand) superfamily, member 14
- domestic cat(101096542) tumor necrosis factor (ligand) superfamily, member 14
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Monoclonal Anti-TNFSF14 antibody produced in mouse, clone 4E3, purified immunoglobulin, buffered aqueous solution,
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immunohistochemistry
immunoprecipitation (IP)
western blot