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Merck
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TNFSF12

tumor necrosis factor (ligand) superfamily, member 12

别名:
APO3L, DR3LG, TWEAK
物种:
Human TNFSF12 (8742), Mouse Tnfsf12 (21944), Rat Tnfsf12 (360548), domestic guinea pig Tnfsf12 (100713543), domestic cat TNFSF12 (101098755), Zebrafish tnfsf12 (567542), dog TNFSF12 (100568280), cow TNFSF12 (100568284), cow TNFSF12 (100551513), Domestic Rabbit TNFSF12 (100356651) ...展开
UniProtKB ID:
O43508, Q8IZK7, Q8WUZ7
基因ID:
  • Human(8742) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
  • Mouse(21944) tumor necrosis factor (ligand) superfamily, member 12
  • Rat(360548) tumor necrosis factor ligand superfamily member 12
  • domestic guinea pig(100713543) tumor necrosis factor (ligand) superfamily, member 12
  • domestic cat(101098755) tumor necrosis factor (ligand) superfamily, member 12
  • Zebrafish(567542) tumor necrosis factor (ligand) superfamily, member 12
  • dog(100568280) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100568284) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100551513) tumor necrosis factor (ligand) superfamily, member 12
  • Domestic Rabbit(100356651) tumor necrosis factor (ligand) superfamily, member 12
  • Horse(100061872) tumor necrosis factor (ligand) superfamily, member 12
  • sheep(101122801) tumor necrosis factor (ligand) superfamily, member 12

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ELISA

货号
说明
物种
RAB0495
小鼠TWEAK ELISA试剂盒, for serum, plasma and cell culture supernatant,
物种
mouse
RAB1765
人TWEAK R ELISA, for serum, plasma and cell culture supernatants,
物种
human
RAB0749
人类 TNFSF12 ELISA 试剂盒, ,
物种
human

Antibodies

货号
说明
物种反应性
应用
HPA004863
Anti-TNFSF13 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
SAB3500423
Anti-TWEAK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
WH0008742M1
Monoclonal Anti-TNFSF12 antibody produced in mouse, clone 4H3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
HPA052967
Anti-TNFSF12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
SAB4700906
Monoclonal Anti-CD255 antibody produced in mouse, clone CARL-1,
物种反应性
human
应用
flow cytometry

Proteins

货号
说明
物种
GF102
TWEAK，人类, Human TWEAK is a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.,
物种
human

esiRNA

货号
说明
物种
EHU227381
MISSION® esiRNA, targeting human TNFSF12,
物种
human
EHU097141
MISSION® esiRNA, targeting human TNFSF12-TNFSF13, TNFSF13,
物种
human