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Merck
CN

TGIF1

TGFB-induced factor homeobox 1

别名:
HPE4, TGIF
物种:
UniProtKB ID:
基因ID:
  • Human(7050) Summary: The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2013]
  • Mouse(21815) TGFB-induced factor homeobox 1
  • Rat(316742) TGFB-induced factor homeobox 1
  • sheep(101105544) TGFB-induced factor homeobox 1
  • cow(510050) TGFB-induced factor homeobox 1
  • Zebrafish(321756) TGFB-induced factor homeobox 1
  • domestic cat(101084747) TGFB-induced factor homeobox 1
  • dog(490537) TGFB-induced factor homeobox 1
  • domestic guinea pig(100716233) TGFB-induced factor homeobox 1
  • chicken(396339) TGFB-induced factor homeobox 1
  • naked mole-rat(101698504) TGFB-induced factor homeobox 1

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Antibodies

货号
说明
物种反应性
应用
Anti-TGIF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
Monoclonal Anti-TGIF antibody produced in mouse, clone 1D12, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Tgif1,
物种
mouse
MISSION® esiRNA, targeting human TGIF1,
物种
human