SMG7
SMG7 nonsense mediated mRNA decay factor
别名:
C1orf16, EST1C, SGA56M
物种:
Human SMG7 (9887), Mouse Smg7 (226517), Rat Smg7 (360855), naked mole-rat Smg7 (101717612), domestic guinea pig Smg7 (100733436), Domestic Rabbit SMG7 (100339791), sheep SMG7 (101105838), cow SMG7 (537131), Horse SMG7 (100055474), domestic cat SMG7 (101088454) ...展开
UniProtKB ID:
基因ID:
- Human(9887) Summary: This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]
- Mouse(226517) Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- Rat(360855) SMG7 nonsense mediated mRNA decay factor
- naked mole-rat(101717612) smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- domestic guinea pig(100733436) smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- Domestic Rabbit(100339791) smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- sheep(101105838) smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- cow(537131) smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- Horse(100055474) smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- domestic cat(101088454) smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- dog(480035) smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- chicken(424444) Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- Zebrafish(565575) Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
- Thale Cress(832060) EST1 domain protein SMG7
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Antibodies
货号
说明
物种反应性
应用
Anti-SMG7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-SMG7 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot