跳转至内容
Merck
CN

SLC7A11

solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11

别名:
CCBR1, xCT
物种:
UniProtKB ID:
基因ID:
  • Human(23657) Summary: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
  • Mouse(26570) solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
  • Rat(310392) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • naked mole-rat(101709765) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • domestic guinea pig(100735308) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • domestic cat(101099374) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • dog(483821) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • chicken(428731) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • sheep(100820755) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • cow(524078) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
产自兔中的抗-SLC7A11抗体, ,
物种反应性
mouse, rat
应用
western blot
Anti-SLC7A11/xCT antibody produced in rabbit, ,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
Anti-SLC7A11 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
抗-SLC7A11 山羊抗, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, rat
应用
ELISA
immunohistochemistry

western blot
Anti-xCT Antibody, clone 3A12, ,
物种反应性
human
应用
immunocytochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SLC7A11,
物种
human