SFTPB
surfactant protein B
PSP-B, SFTB3, SFTP3, SMDP1, SP-B
Human SFTPB (6439), Mouse Sftpb (20388), Rat Sftpb (192155), naked mole-rat Sftpb (101700017), domestic guinea pig Sftpb (100379548), dog SFTPB (100688334), Horse SFTPB (100034028), domestic cat SFTPB (101091359), sheep SFTPB (443043), cow SFTPB (507398)
- Human(6439) Summary: This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]
- Mouse(20388) surfactant associated protein B
- Rat(192155) surfactant protein B
- naked mole-rat(101700017) surfactant protein B
- domestic guinea pig(100379548) surfactant associated protein B
- dog(100688334) surfactant protein B
- Horse(100034028) surfactant protein B
- domestic cat(101091359) surfactant protein B
- sheep(443043) surfactant protein B
- cow(507398) surfactant protein B
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Antibodies
Anti-SP-B (Surfactant protein B) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM370, purified immunoglobulin,
human
immunohistochemistry
western blot
western blot
Anti-Surfactant Protein B Antibody, from rabbit, purified by affinity chromatography,
human, mouse, rat
immunohistochemistry
western blot
western blot
Anti-SFTPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
Anti-SFTPB antibody produced in rabbit, affinity isolated antibody,
dog, guinea pig, human, rat
immunohistochemistry
western blot
western blot
抗Prosurfactant蛋白B抗体,可与CT和NT反应, serum, Chemicon®,
human, mouse
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot