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Merck
CN

SFTPB

surfactant protein B

别名:
PSP-B, SFTB3, SFTP3, SMDP1, SP-B
物种:
UniProtKB ID:
基因ID:
  • Human(6439) Summary: This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]
  • Mouse(20388) surfactant associated protein B
  • Rat(192155) surfactant protein B
  • naked mole-rat(101700017) surfactant protein B
  • domestic guinea pig(100379548) surfactant associated protein B
  • dog(100688334) surfactant protein B
  • Horse(100034028) surfactant protein B
  • domestic cat(101091359) surfactant protein B
  • sheep(443043) surfactant protein B
  • cow(507398) surfactant protein B

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Antibodies

货号
说明
物种反应性
应用
Anti-SP-B (Surfactant protein B) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM370, purified immunoglobulin,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-Surfactant Protein B Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-SFTPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-SFTPB antibody produced in rabbit, affinity isolated antibody,
物种反应性
dog, guinea pig, human, rat
应用
immunohistochemistry
western blot
抗Prosurfactant蛋白B抗体,可与CT和NT反应, serum, Chemicon®,
物种反应性
human, mouse
应用
ELISA
immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SFTPB,
物种
human