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Merck
CN

RNF8

ring finger protein 8, E3 ubiquitin protein ligase

别名:
hRNF8
物种:
UniProtKB ID:
基因ID:
  • Human(9025) Summary: The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
  • Mouse(58230) ring finger protein 8
  • Rat(361815) ring finger protein 8, E3 ubiquitin protein ligase
  • naked mole-rat(101703952) ring finger protein 8, E3 ubiquitin protein ligase
  • domestic guinea pig(100725403) ring finger protein 8, E3 ubiquitin protein ligase
  • sheep(101103680) ring finger protein 8, E3 ubiquitin protein ligase
  • chicken(421435) ring finger protein 8, E3 ubiquitin protein ligase
  • domestic cat(101082654) ring finger protein 8, E3 ubiquitin protein ligase
  • dog(481775) ring finger protein 8, E3 ubiquitin protein ligase
  • Zebrafish(404050) ring finger protein 8, E3 ubiquitin protein ligase
  • cow(515933) ring finger protein 8

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Antibodies

货号
说明
物种反应性
应用
抗RNF8 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-RNF8 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, horse, human, mouse, pig, rat
应用
immunohistochemistry
western blot
抗环指蛋白8抗体, from rabbit, purified by affinity chromatography,
物种反应性
chimpanzee, human, mouse, rhesus macaque
应用
immunocytochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human RNF8,
物种
human