RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
LCA13, LCA3, RP53, SDR7C2
Human RDH12 (145226), Mouse Rdh12 (77974), Rat Rdh12 (314264), cow RDH12 (369021), domestic cat RDH12 (101093615), domestic guinea pig Rdh12 (100718599), chicken RDH12 (423274), naked mole-rat Rdh12 (101715642), sheep RDH12 (101115797), dog RDH12 (490744)
- Human(145226) Summary: The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). [provided by RefSeq, Jul 2008]
- Mouse(77974) retinol dehydrogenase 12
- Rat(314264) retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
- cow(369021) retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
- domestic cat(101093615) retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
- domestic guinea pig(100718599) retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
- chicken(423274) retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
- naked mole-rat(101715642) retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
- sheep(101115797) retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
- dog(490744) retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
- Zebrafish(436597) retinol dehydrogenase 12 (all-trans and 9-cis)
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Antibodies
Monoclonal Anti-RDH12 antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
human
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-RDH12 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
human
western blot
Anti-RDH12 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
human
western blot