PYCARD
PYD and CARD domain containing
别名:
ASC, CARD5, TMS, TMS-1, TMS1
物种:
Human PYCARD (29108), Mouse Pycard (66824), Rat Pycard (282817), Goat PYCARD (100861338), domestic guinea pig Pycard (100734858), domestic cat PYCARD (101088449), sheep PYCARD (101105208), dog PYCARD (489925), Zebrafish pycard (57923), cow PYCARD (282846)
UniProtKB ID:
基因ID:
- Human(29108) Summary: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(66824) PYD and CARD domain containing
- Rat(282817) PYD and CARD domain containing
- Goat(100861338) PYD and CARD domain containing
- domestic guinea pig(100734858) PYD and CARD domain containing
- domestic cat(101088449) PYD and CARD domain containing
- sheep(101105208) PYD and CARD domain containing
- dog(489925) PYD and CARD domain containing
- Zebrafish(57923) PYD and CARD domain containing
- cow(282846) PYD and CARD domain containing
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Antibodies
货号
说明
物种反应性
应用
抗-ASC 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ASC/TMS1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
western blot
western blot
Anti-PYCARD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ASC/TMS1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
货号
说明
物种