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Merck
CN

PTPRN2

protein tyrosine phosphatase, receptor type, N polypeptide 2

别名:
IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2
物种:
UniProtKB ID:
基因ID:
  • Human(5799) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(19276) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • Rat(29714) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • Zebrafish(325033) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • domestic cat(101089683) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • naked mole-rat(101716326) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • domestic guinea pig(100723726) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • Horse(100067294) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • chicken(420449) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • dog(482825) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • Domestic Rabbit(100340246) protein tyrosine phosphatase, receptor type, N polypeptide 2
  • cow(616515) protein tyrosine phosphatase, receptor type, N polypeptide 2

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Antibodies

货号
说明
物种反应性
应用
Anti-PTPRN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
抗PTPRN2 小鼠抗, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-PTPRN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-PTPRN2 antibody produced in mouse, clone 7F8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PTPRN2,
物种
human
MISSION® esiRNA, targeting mouse Ptprn2,
物种
mouse