PTK2B
protein tyrosine kinase 2 beta
别名:
CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK
物种:
Human PTK2B (2185), Mouse Ptk2b (19229), Rat Ptk2b (50646), domestic cat PTK2B (101091691), dog PTK2B (486102), chicken PTK2B (421998), domestic guinea pig Ptk2b (100734027), naked mole-rat Ptk2b (101714384), cow PTK2B (541008), sheep PTK2B (101106906) ...展开
UniProtKB ID:
基因ID:
- Human(2185) Summary: This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19229) PTK2 protein tyrosine kinase 2 beta
- Rat(50646) protein tyrosine kinase 2 beta
- domestic cat(101091691) PTK2B protein tyrosine kinase 2 beta
- dog(486102) PTK2B protein tyrosine kinase 2 beta
- chicken(421998) PTK2B protein tyrosine kinase 2 beta
- domestic guinea pig(100734027) protein tyrosine kinase 2 beta
- naked mole-rat(101714384) protein tyrosine kinase 2 beta
- cow(541008) PTK2B protein tyrosine kinase 2 beta
- sheep(101106906) PTK2B protein tyrosine kinase 2 beta
- Domestic Rabbit(100342358) PTK2B protein tyrosine kinase 2 beta
- Horse(100054547) PTK2B protein tyrosine kinase 2 beta
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ELISA
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-Pyk2 Antibody, Upstate®, from rabbit,
物种反应性
human, mouse
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-PTK2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
物种反应性
human, rat
应用
immunohistochemistry
western blot
western blot
Anti-Pyk2/PTK2B Antibody, clone 3B7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-PTK2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-PTK2B (Ab-402) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
货号
说明
物种
Pyk2 Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Pyk2. For use in Kinase Assays.,
物种
human