跳转至内容
Merck
CN

PSMF1

proteasome (prosome, macropain) inhibitor subunit 1 (PI31)

别名:
PI31
物种:
UniProtKB ID:
基因ID:
  • Human(9491) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(228769) proteasome (prosome, macropain) inhibitor subunit 1
  • Rat(689852) proteasome (prosome, macropain) inhibitor subunit 1
  • domestic guinea pig(100732045) proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
  • naked mole-rat(101699766) proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
  • sheep(101120937) proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
  • chicken(430115) proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
  • cow(617807) proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
  • dog(477184) proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
  • Zebrafish(436820) proteasome (prosome, macropain) inhibitor subunit 1
  • domestic cat(101101124) proteasome (prosome, macropain) inhibitor subunit 1 (PI31)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-PSMF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-PSMF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PSMF1,
物种
human
MISSION® esiRNA, targeting mouse Psmf1,
物种
mouse