PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
AF, AF-1, ASF, MCB1, Rpn10, S5A, pUB-R5
Human PSMD4 (5710), Mouse Psmd4 (19185), Rat Psmd4 (83499), dog PSMD4 (100192385), domestic cat PSMD4 (101098564), chicken PSMD4 (100216364), naked mole-rat Psmd4 (101702092), domestic guinea pig Psmd4 (101788278), sheep PSMD4 (100101235), Domestic Rabbit PSMD4 (100328669) ...展开
- Human(5710) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq, Jul 2008]
- Mouse(19185) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- Rat(83499) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- dog(100192385) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- domestic cat(101098564) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- chicken(100216364) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- naked mole-rat(101702092) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- domestic guinea pig(101788278) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- sheep(100101235) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- Domestic Rabbit(100328669) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- cow(282016) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
- Horse(100216429) proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
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Antibodies
Anti-PSMD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PSMD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-19S regulator non-ATPase subunit S5a/Rpn10 Antibody, clone S5a-18, clone S5a-18, Upstate®, from mouse,
human
immunoprecipitation (IP)
western blot
western blot
Anti-PSMD4 antibody produced in rabbit, affinity isolated antibody,
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
western blot
Anti-PSMD4 (AB1) antibody produced in rabbit, affinity isolated antibody,
bovine, horse, human, pig, rabbit, rat, sheep
immunohistochemistry
western blot
western blot