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Merck
CN

PSMD12

proteasome (prosome, macropain) 26S subunit, non-ATPase, 12

别名:
Rpn5, p55
物种:
UniProtKB ID:
基因ID:
  • Human(5718) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. [provided by RefSeq, Jul 2008]
  • Mouse(66997) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • Rat(287772) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • dog(480465) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • domestic cat(101100851) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • cow(538204) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • Domestic Rabbit(100338269) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • sheep(101107714) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • chicken(417425) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • naked mole-rat(101714054) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • domestic guinea pig(100719676) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • Zebrafish(321898) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12

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Antibodies

货号
说明
物种反应性
应用
抗-PSMD12 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-PSMD12 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PSMD12,
物种
human