PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
别名:
P112, Rpn2, S1
物种:
Human PSMD1 (5707), Mouse Psmd1 (70247), Rat Psmd1 (83806), dog PSMD1 (100683530), sheep PSMD1 (101122259), Zebrafish psmd1 (554967), naked mole-rat Psmd1 (101699553), cow PSMD1 (511803), Horse PSMD1 (100057015), chicken PSMD1 (424926)
UniProtKB ID:
基因ID:
- Human(5707) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2010]
- Mouse(70247) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
- Rat(83806) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
- dog(100683530) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
- sheep(101122259) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
- Zebrafish(554967) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
- naked mole-rat(101699553) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
- cow(511803) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
- Horse(100057015) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
- chicken(424926) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
- domestic guinea pig(100736234) proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
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Antibodies
货号
说明
物种反应性
应用
Anti-PSMD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PSMD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-PSMD1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot