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Merck
CN

PRCP

prolylcarboxypeptidase (angiotensinase C)

别名:
HUMPCP, PCP
物种:
UniProtKB ID:
基因ID:
  • Human(5547) Summary: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(72461) prolylcarboxypeptidase (angiotensinase C)
  • Rat(293118) prolylcarboxypeptidase (angiotensinase C)
  • sheep(101107644) prolylcarboxypeptidase (angiotensinase C)
  • Horse(100061830) prolylcarboxypeptidase (angiotensinase C)
  • domestic cat(101100665) prolylcarboxypeptidase (angiotensinase C)
  • cow(534927) prolylcarboxypeptidase (angiotensinase C)
  • naked mole-rat(101719590) prolylcarboxypeptidase (angiotensinase C)
  • chicken(428096) prolylcarboxypeptidase (angiotensinase C)
  • dog(476788) prolylcarboxypeptidase (angiotensinase C)
  • Zebrafish(436967) prolylcarboxypeptidase (angiotensinase C)
  • domestic guinea pig(100734342) prolylcarboxypeptidase (angiotensinase C)

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ELISA

货号
说明
物种
人PRCP ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
western blot

Proteins

货号
说明
物种
PrCP active human, recombinant, expressed in FreeStyle 293-F cells, ≥15% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PRCP,
物种
human
MISSION® esiRNA, targeting mouse Prcp,
物种
mouse