PGC
progastricsin (pepsinogen C)
别名:
PEPC, PGII
物种:
Human PGC (5225), Mouse Pgc (109820), Rat Pgc (24864), fruit fly pgc (5740599), chicken PGC (395690), domestic cat PGC (101100053), dog PGC (609052), sheep PGC (101106633), cow PGC (514502), Domestic Rabbit PGC (100009323) ...展开
UniProtKB ID:
基因ID:
- Human(5225) Summary: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
- Mouse(109820) progastricsin (pepsinogen C)
- Rat(24864) progastricsin (pepsinogen C)
- fruit fly(5740599) polar granule component
- chicken(395690) progastricsin (pepsinogen C)
- domestic cat(101100053) progastricsin (pepsinogen C)
- dog(609052) progastricsin (pepsinogen C)
- sheep(101106633) progastricsin (pepsinogen C)
- cow(514502) progastricsin (pepsinogen C)
- Domestic Rabbit(100009323) progastricsin (pepsinogen C)
- naked mole-rat(101713573) progastricsin (pepsinogen C)
- domestic guinea pig(100135598) progastricsin (pepsinogen C)
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Antibodies
货号
说明
物种反应性
应用
Anti-PGC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-PGC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-PGC antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-PGC antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
esiRNA
货号
说明
物种