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Merck
CN

PDK2

pyruvate dehydrogenase kinase, isozyme 2

别名:
PDHK2, PDKII
物种:
Human PDK2 (5164), Mouse Pdk2 (18604), Rat Pdk2 (81530), domestic guinea pig Pdk2 (100734517), Zebrafish pdk2 (393971), cow PDK2 (524075), domestic cat PDK2 (101100013), dog PDK2 (491075), sheep PDK2 (101108929), naked mole-rat Pdk2 (101699994)
UniProtKB ID:
Q15119, A8K3A7, B3KNW0, Q6P515, Q9BS05
基因ID:
  • Human(5164) Summary: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(18604) pyruvate dehydrogenase kinase, isoenzyme 2
  • Rat(81530) pyruvate dehydrogenase kinase, isozyme 2
  • domestic guinea pig(100734517) pyruvate dehydrogenase kinase, isozyme 2
  • Zebrafish(393971) pyruvate dehydrogenase kinase, isoenzyme 2
  • cow(524075) pyruvate dehydrogenase kinase, isozyme 2
  • domestic cat(101100013) pyruvate dehydrogenase kinase, isozyme 2
  • dog(491075) pyruvate dehydrogenase kinase, isozyme 2
  • sheep(101108929) pyruvate dehydrogenase kinase, isozyme 2
  • naked mole-rat(101699994) pyruvate dehydrogenase kinase, isozyme 2

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Antibodies

货号
说明
物种反应性
应用
SAB4502155
Anti-PDK2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
ST1643
Anti-PDK2 Mouse mAb (2G1), liquid, clone 2G1, Calbiochem®,
物种反应性
human
应用
SAB5701559
Anti-PDK2 antibody produced in rabbit, ,
物种反应性
human, rat
应用
immunohistochemistry
western blot
WH0005164M2
Monoclonal Anti-PDK2 antibody produced in mouse, clone 5F8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
HPA008287
Anti-PDK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

货号
说明
物种
347795
二氯乙酸钠, 98%,
物种
human

Proteins

货号
说明
物种
SRP5248
PDHK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EMU052061
MISSION® esiRNA, targeting mouse Pdk2,
物种
mouse
EHU028791
MISSION® esiRNA, targeting human PDK2,
物种
human