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Merck
CN

PCDHGB1

protocadherin gamma subfamily B, 1

别名:
PCDH-GAMMA-B1
物种:
UniProtKB ID:
基因ID:
  • Human(56104) Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  • Mouse(93699) protocadherin gamma subfamily B, 1
  • cow(100848177) protocadherin gamma subfamily B, 1
  • dog(607540) protocadherin gamma subfamily B, 1
  • domestic cat(101097450) protocadherin gamma subfamily B, 1
  • naked mole-rat(101699132) protocadherin gamma subfamily B, 1
  • sheep(101102813) protocadherin gamma subfamily B, 1
  • domestic guinea pig(100720280) protocadherin gamma subfamily B, 1

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Antibodies

货号
说明
物种反应性
应用
Anti-PCDHGB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-PCDHGB1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot