NR1I2
nuclear receptor subfamily 1, group I, member 2
别名:
BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR
物种:
Human NR1I2 (8856), Mouse Nr1i2 (18171), Rat Nr1i2 (84385), sheep NR1I2 (101118075), cow NR1I2 (493713), domestic cat NR1I2 (101088355), dog NR1I2 (403482), Zebrafish nr1i2 (565875), naked mole-rat Nr1i2 (101722589), domestic guinea pig Nr1i2 (100719967)
UniProtKB ID:
基因ID:
- Human(8856) Summary: This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]
- Mouse(18171) nuclear receptor subfamily 1, group I, member 2
- Rat(84385) nuclear receptor subfamily 1, group I, member 2
- sheep(101118075) nuclear receptor subfamily 1, group I, member 2
- cow(493713) nuclear receptor subfamily 1, group I, member 2
- domestic cat(101088355) nuclear receptor subfamily 1, group I, member 2
- dog(403482) nuclear receptor subfamily 1, group I, member 2
- Zebrafish(565875) nuclear receptor subfamily 1, group I, member 2
- naked mole-rat(101722589) nuclear receptor subfamily 1, group I, member 2
- domestic guinea pig(100719967) nuclear receptor subfamily 1, group I, member 2
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Antibodies
货号
说明
物种反应性
应用
Anti-NR1I2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-NR1I2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-NR1I2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-PXR Antibody, clone 1F10.1, clone 1F10.1, from mouse,
物种反应性
chimpanzee, gorilla, human
应用
western blot
Anti-NR1I2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, rat
应用
immunofluorescence
western blot
western blot
Proteins
esiRNA
货号
说明
物种