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Merck
CN

NOD2

nucleotide-binding oligomerization domain containing 2

别名:
ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
物种:
UniProtKB ID:
基因ID:
  • Human(64127) Summary: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(257632) nucleotide-binding oligomerization domain containing 2
  • Rat(291912) nucleotide-binding oligomerization domain containing 2
  • Domestic Rabbit(100356594) nucleotide-binding oligomerization domain containing 2
  • sheep(780465) nucleotide-binding oligomerization domain containing 2
  • cow(444867) nucleotide-binding oligomerization domain containing 2
  • dog(487286) nucleotide-binding oligomerization domain containing 2
  • domestic cat(101096863) nucleotide-binding oligomerization domain containing 2
  • naked mole-rat(101709371) nucleotide-binding oligomerization domain containing 2
  • domestic guinea pig(100727812) nucleotide-binding oligomerization domain containing 2
  • Zebrafish(777696) nucleotide-binding oligomerization domain containing 2

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Antibodies

货号
说明
物种反应性
应用
抗-NOD2抗体,克隆2D9, clone 2D9, from mouse,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-NOD2 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-NOD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Nod2,
物种
mouse
MISSION® esiRNA, targeting human NOD2,
物种
human