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Merck
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MTA1

metastasis associated 1

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(9112) Summary: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(116870) metastasis associated 1
  • Rat(64520) metastasis associated 1
  • domestic guinea pig(100731798) metastasis associated 1
  • naked mole-rat(101721757) metastasis associated 1
  • chicken(429060) metastasis associated 1
  • domestic cat(101090194) metastasis associated 1
  • Horse(100146742) metastasis associated 1
  • dog(480450) metastasis associated 1
  • cow(511438) metastasis associated 1

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Antibodies

货号
说明
物种反应性
应用
Anti-MTA1 Antibody, clone 1G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
guinea pig, human, monkey, mouse, rat
应用
affinity binding assay
immunohistochemistry

western blot
Anti-MTA1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
immunoprecipitation (IP)
microarray

western blot
Anti-MTA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Monoclonal Anti-MTA1 antibody produced in mouse, clone 4D11, purified immunoglobulin, buffered aqueous solution,
物种反应性
mouse
应用
ELISA
immunofluorescence

western blot
Monoclonal Anti-MTA1 antibody produced in mouse, clone 4D5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human MTA1,
物种
human
MISSION® esiRNA, targeting mouse Mta1,
物种
mouse