MLH1
mutL homolog 1
别名:
COCA2, FCC2, HNPCC, HNPCC2, hMLH1
物种:
Human MLH1 (4292), Mouse Mlh1 (17350), Rat Mlh1 (81685), Thale Cress MLH1 (826493), fruit fly Mlh1 (35796), sheep MLH1 (101108344), domestic guinea pig Mlh1 (100717848), naked mole-rat Mlh1 (101698546), Domestic Rabbit MLH1 (100337912), Horse MLH1 (100050351) ...展开
UniProtKB ID:
基因ID:
- Human(4292) Summary: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]
- Mouse(17350) mutL homolog 1 (E. coli)
- Rat(81685) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- Thale Cress(826493) DNA mismatch repair protein MLH1
- fruit fly(35796) CG11482 gene product from transcript CG11482-RB
- sheep(101108344) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- domestic guinea pig(100717848) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- naked mole-rat(101698546) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- Domestic Rabbit(100337912) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- Horse(100050351) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- cow(533652) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- dog(477019) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- domestic cat(101089037) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- Zebrafish(393632) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- chicken(420729) mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
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Antibodies
货号
说明
物种反应性
应用
Monoclonal Anti-MLH1 antibody produced in mouse, clone M1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
Anti-MLH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-MLH1 Antibody, clone 1B15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-MLH1 antibody produced in mouse, clone 4C9C7, ascites fluid,
物种反应性
human, monkey
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-MLH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence