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Merck
CN

LOXL3

lysyl oxidase-like 3

别名:
LOXL
物种:
UniProtKB ID:
基因ID:
  • Human(84695) Summary: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(16950) lysyl oxidase-like 3
  • Rat(312478) lysyl oxidase-like 3
  • dog(483101) lysyl oxidase-like 3
  • Zebrafish(553538) LOXL3 protein
  • cow(613599) lysyl oxidase-like 3
  • chicken(425986) lysyl oxidase-like 3
  • domestic cat(101087470) lysyl oxidase-like 3
  • domestic guinea pig(100733784) lysyl oxidase-like 3
  • Horse(100053584) lysyl oxidase-like 3
  • naked mole-rat(101726484) lysyl oxidase-like 3
  • sheep(101119969) lysyl oxidase-like 3

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Antibodies

货号
说明
物种反应性
应用
Anti-LOXL3, affinity isolated antibody,
物种反应性
human, mouse
应用
immunohistochemistry
ANTI-LOXL3 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
immunohistochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human LOXL3,
物种
human