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Merck
CN

LMNA

lamin A/C

别名:
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1
物种:
Human LMNA (4000), Mouse Lmna (16905), Rat Lmna (60374), domestic guinea pig Lmna (100735212), chicken LMNA (415464), sheep LMNA (101107924), cow LMNA (404144), domestic cat LMNA (101086199), Horse LMNA (100057663), dog LMNA (480124) ...展开
UniProtKB ID:
P02545, B4DI32, D3DVB0, E7EUI9, P02546, Q5TCJ2, Q5TCJ3, Q969I8
基因ID:
  • Human(4000) Summary: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
  • Mouse(16905) lamin A
  • Rat(60374) lamin A/C
  • domestic guinea pig(100735212) lamin A/C
  • chicken(415464) lamin A/C
  • sheep(101107924) lamin A/C
  • cow(404144) lamin A/C
  • domestic cat(101086199) lamin A/C
  • Horse(100057663) lamin A/C
  • dog(480124) lamin A/C
  • Zebrafish(195815) lamin A
  • naked mole-rat(101704567) lamin A/C

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Antibodies

货号
说明
物种反应性
应用
05-1231
早老蛋白抗体，克隆13A4, clone 13A4, Upstate®, from mouse,
物种反应性
human
应用
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
MABT858
抗前核纤层蛋白A抗体，克隆PL-1C7, clone PL-1C7, from mouse,
物种反应性
human, mouse
应用
ELISA
flow cytometry
immunocytochemistry
western blot
MABT1341
Anti-Lamin A/C Antibody, clone 4C11, clone 4C11, from mouse,
物种反应性
syrian hamster, human, monkey, mouse, rat
应用
ChIP
immunofluorescence
immunoprecipitation (IP)
western blot
SAB4200272
Anti-Progerin antibody, Mouse monoclonal, clone 13A4, purified from hybridoma cell culture,
物种反应性
human
应用
immunofluorescence
immunoprecipitation (IP)
western blot
SAB4200420
Anti-Lamin A, mature antibody, Mouse monoclonal, clone 4A4, purified from hybridoma cell culture,
物种反应性
human
应用
immunofluorescence
western blot

esiRNA

货号
说明
物种
EHU063791
MISSION® esiRNA, targeting human LMNA,
物种
human
EMU056191
MISSION® esiRNA, targeting mouse Lmna,
物种
mouse