LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
别名:
SCDO3
物种:
Human LFNG (3955), Mouse Lfng (16848), Rat Lfng (170905), naked mole-rat Lfng (101699763), domestic guinea pig Lfng (100730084), Zebrafish lfng (30158), chicken LFNG (395790), dog LFNG (489891), cow LFNG (516209), sheep LFNG (101112372)
UniProtKB ID:
基因ID:
- Human(3955) Summary: This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(16848) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Rat(170905) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- naked mole-rat(101699763) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- domestic guinea pig(100730084) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Zebrafish(30158) lunatic fringe homolog
- chicken(395790) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- dog(489891) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- cow(516209) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- sheep(101112372) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
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Antibodies
货号
说明
物种反应性
应用
抗-LFNG 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Monoclonal Anti-LFNG antibody produced in mouse, clone 2D10-3C11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-LFNG antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Monoclonal Anti-LFNG antibody produced in mouse, clone 4F8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)
immunoprecipitation (IP)
Monoclonal Anti-LFNG antibody produced in mouse, clone 3B5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
esiRNA
货号
说明
物种