KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
别名:
KCa2.1, SK1, SKCA1, hSK1
物种:
Human KCNN1 (3780), Mouse Kcnn1 (84036), Rat Kcnn1 (54261), naked mole-rat Kcnn1 (101717556), domestic guinea pig Kcnn1 (100715012), sheep KCNN1 (101112056), dog KCNN1 (484829), domestic cat KCNN1 (101085608), cow KCNN1 (408008)
UniProtKB ID:
基因ID:
- Human(3780) Summary: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008]
- Mouse(84036) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
- Rat(54261) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
- naked mole-rat(101717556) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
- domestic guinea pig(100715012) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
- sheep(101112056) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
- dog(484829) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
- domestic cat(101085608) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
- cow(408008) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
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