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Merck
CN

ITM2B

integral membrane protein 2B

别名:
ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, imBRI2
物种:
UniProtKB ID:
基因ID:
  • Human(9445) Summary: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]
  • Mouse(16432) integral membrane protein 2B
  • Rat(290364) integral membrane protein 2B
  • chicken(395969) integral membrane protein 2B
  • naked mole-rat(101704426) integral membrane protein 2B
  • domestic guinea pig(100716017) integral membrane protein 2B
  • sheep(100174988) integral membrane protein 2B
  • cow(510575) integral membrane protein 2B
  • dog(476916) integral membrane protein 2B

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Antibodies

货号
说明
物种反应性
应用
Anti-ITM2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-ITM2B antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-ITM2B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-ITM2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Monoclonal Anti-ITM2B antibody produced in mouse, clone 1A10, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Itm2b,
物种
mouse
MISSION® esiRNA, targeting human ITM2B,
物种
human