IL4R
interleukin 4 receptor
别名:
CD124, IL-4RA, IL4RA
物种:
Human IL4R (3566), Rat Il4r (25084), cow IL4R (404154), domestic guinea pig Il4r (100721566), sheep IL4R (101109063), Horse IL4R (791252), domestic cat IL4R (101096277), Zebrafish il4r (503594), dog IL4R (489957), Domestic Rabbit IL4R (100337721) ...展开
UniProtKB ID:
基因ID:
- Human(3566) Summary: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
- Rat(25084) interleukin 4 receptor
- cow(404154) interleukin 4 receptor
- domestic guinea pig(100721566) interleukin 4 receptor
- sheep(101109063) interleukin 4 receptor
- Horse(791252) interleukin 4 receptor
- domestic cat(101096277) interleukin 4 receptor
- Zebrafish(503594) interleukin 4 receptor
- dog(489957) interleukin 4 receptor
- Domestic Rabbit(100337721) interleukin 4 receptor
- chicken(416585) interleukin 4 receptor
- naked mole-rat(101704138) interleukin 4 receptor
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ELISA
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-IL-4R antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-IL4R antibody produced in mouse, clone 1D3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Anti-IL4R antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
flow cytometry
western blot
western blot
Anti-Interleukin-4 Soluble Receptor antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
物种反应性
human
应用
ELISA
neutralization
western blot
neutralization
western blot
Anti-IL4R antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
esiRNA
货号
说明
物种