IDO1
indoleamine 2,3-dioxygenase 1
别名:
IDO, IDO-1, INDO
物种:
Human IDO1 (3620), Mouse Ido1 (15930), Rat Ido1 (66029), Zebrafish ido1 (571967), dog IDO1 (475574), domestic guinea pig Ido1 (100728309), naked mole-rat Ido1 (101723745), domestic cat IDO1 (101096977), cow IDO1 (506281), sheep IDO1 (100196903)
UniProtKB ID:
基因ID:
- Human(3620) Summary: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
- Mouse(15930) indoleamine 2,3-dioxygenase 1
- Rat(66029) indoleamine 2,3-dioxygenase 1
- Zebrafish(571967) indoleamine 2,3-dioxygenase 1
- dog(475574) indoleamine 2,3-dioxygenase 1
- domestic guinea pig(100728309) indoleamine 2,3-dioxygenase 1
- naked mole-rat(101723745) indoleamine 2,3-dioxygenase 1
- domestic cat(101096977) indoleamine 2,3-dioxygenase 1
- cow(506281) indoleamine 2,3-dioxygenase 1
- sheep(100196903) indoleamine 2,3-dioxygenase 1
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Antibodies
货号
说明
物种反应性
应用
Anti-IDO1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
抗-IDO1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
抗-吲哚胺2,3-双加氧酶抗体，克隆10.1, clone 10.1, Chemicon®, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
抗-IDO-1抗体，克隆4B7 | MABF850, clone 4B7, from mouse,
物种反应性
mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-Ido1, clone 8G11 Antibody, clone 8G11, from mouse,
物种反应性
mouse
应用
flow cytometry
western blot
western blot
Proteins
货号
说明
物种