跳转至内容
Merck
CN

IDH3A

isocitrate dehydrogenase 3 (NAD+) alpha

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(3419) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008]
  • Mouse(67834) isocitrate dehydrogenase 3 (NAD+) alpha
  • Rat(114096) isocitrate dehydrogenase 3 (NAD+) alpha
  • chicken(415362) isocitrate dehydrogenase 3 (NAD+) alpha
  • domestic guinea pig(100720114) isocitrate dehydrogenase 3 (NAD+) alpha
  • naked mole-rat(101706503) isocitrate dehydrogenase 3 (NAD+) alpha
  • domestic cat(101085721) isocitrate dehydrogenase 3 (NAD+) alpha
  • cow(282446) isocitrate dehydrogenase 3 (NAD+) alpha
  • sheep(101120868) isocitrate dehydrogenase 3 (NAD+) alpha
  • dog(479066) isocitrate dehydrogenase 3 (NAD+) alpha
  • Zebrafish(393926) isocitrate dehydrogenase 3 (NAD+) alpha

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-IDH3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
Anti-IDH3A antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-IDH3A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, rat
应用
immunofluorescence
western blot
Anti-IDH3A (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, canine, human, mouse, pig, rat
应用
ELISA
western blot
Anti-IDH3A antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot

Small Molecule - Cofactor

货号
说明
物种
NAD Cofactor, Can be used as a cofactor in reactions with NAD-dependent histone deacetylase enzymes.,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Idh3a,
物种
mouse
MISSION® esiRNA, targeting human IDH3A,
物种
human