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Merck
CN

HDAC1

histone deacetylase 1

别名:
GON-10, HD1, RPD3, RPD3L1
物种:
Human HDAC1 (3065), Mouse Hdac1 (433759), Rat Hdac1 (297893), chicken HDAC1 (373961), cow HDAC1 (404126), sheep HDAC1 (100820752), Zebrafish hdac1 (192302), domestic cat HDAC1 (101099228), naked mole-rat Hdac1 (101715102), domestic guinea pig Hdac1 (100728529)
UniProtKB ID:
Q13547, Q92534
基因ID:
  • Human(3065) Summary: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(433759) histone deacetylase 1
  • Rat(297893) histone deacetylase 1
  • chicken(373961) histone deacetylase 1
  • cow(404126) histone deacetylase 1
  • sheep(100820752) histone deacetylase 1
  • Zebrafish(192302) histone deacetylase 1
  • domestic cat(101099228) histone deacetylase 1
  • naked mole-rat(101715102) histone deacetylase 1
  • domestic guinea pig(100728529) histone deacetylase 1
  • dog(487309) histone deacetylase 1

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Activity Assay

货号
说明
物种
CS1010
组蛋白去乙酰化酶检测试剂盒，荧光分析法, sufficient for 100 assays (96 well plates),
物种
human

Small Molecule - Antagonist

货号
说明
物种
B103500
丁酸, ≥99%,
物种
human
W222119
丁酸, natural, ≥99%, FCC, FG,
物种
human
W222100
丁酸, ≥99%, FG,
物种
human
P6273
2-丙基戊酸, ,
物种
rat, human, mouse

Antibodies

货号
说明
物种反应性
应用
HPA029693
Anti-HDAC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
AMAB90781
Monoclonal Anti-HDAC1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0510, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
AV38530
Anti-HDAC1 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, dog, guinea pig, human, mouse, rat
应用
western blot
SAB4501383
Anti-HDAC1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB2101020
Anti-HDAC1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, yeast
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
SML0061
SAHA, ≥98% (HPLC),
物种
human
P6273
2-丙基戊酸, ,
物种
rat, human, mouse
SML1175
罗咪酯肽, ≥98% (HPLC),
物种
human
C0621
CI−994, ≥98% (HPLC), powder,
物种
human

Proteins

货号
说明
物种
SRP0100
HDAC-1 human, recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE),
物种
human
SRP0101
HDAC 1 from Plasmodium falciparum, recombinant, expressed in baculovirus infected insect cells, ≥40% (SDS-PAGE),
物种
SRP5265
HDAC1, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EHU025841
MISSION® esiRNA, targeting human HDAC1,
物种
human