GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
GPD-C, GPDH-C, HTGTI
Human GPD1 (2819), Mouse Gpd1 (14555), Rat Gpd1 (60666), domestic guinea pig Gpd1 (100720368), naked mole-rat Gpd1 (101702723), Horse GPD1 (100052204), domestic cat GPD1 (101086577), dog GPD1 (607942), cow GPD1 (525042), sheep GPD1 (101119894)
- Human(2819) Summary: This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
- Mouse(14555) glycerol-3-phosphate dehydrogenase 1 (soluble)
- Rat(60666) glycerol-3-phosphate dehydrogenase 1 (soluble)
- domestic guinea pig(100720368) glycerol-3-phosphate dehydrogenase 1 (soluble)
- naked mole-rat(101702723) glycerol-3-phosphate dehydrogenase 1 (soluble)
- Horse(100052204) glycerol-3-phosphate dehydrogenase 1 (soluble)
- domestic cat(101086577) glycerol-3-phosphate dehydrogenase 1 (soluble)
- dog(607942) glycerol-3-phosphate dehydrogenase 1 (soluble)
- cow(525042) glycerol-3-phosphate dehydrogenase 1 (soluble)
- sheep(101119894) glycerol-3-phosphate dehydrogenase 1 (soluble)
- chicken(424263) glycerol-3-phosphate dehydrogenase 1 (soluble)
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