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GNB3

guanine nucleotide binding protein (G protein), beta polypeptide 3

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(2784) Summary: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described. [provided by RefSeq, Jul 2008]
  • Mouse(14695) guanine nucleotide binding protein (G protein), beta 3
  • Rat(60449) guanine nucleotide binding protein (G protein), beta polypeptide 3
  • naked mole-rat(101718903) guanine nucleotide binding protein (G protein), beta polypeptide 3
  • domestic guinea pig(100725705) guanine nucleotide binding protein (G protein), beta polypeptide 3
  • cow(513340) guanine nucleotide binding protein (G protein), beta polypeptide 3
  • sheep(101110493) guanine nucleotide binding protein (G protein), beta polypeptide 3
  • chicken(427945) guanine nucleotide binding protein (G protein), beta polypeptide 3
  • dog(403511) guanine nucleotide binding protein (G protein), beta polypeptide 3
  • domestic cat(101084799) guanine nucleotide binding protein (G protein), beta polypeptide 3

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Antibodies

货号
说明
物种反应性
应用
Anti-GNB3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GNB3,
物种
human